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Health Protection Agency:

Investigations into anti–viral drug susceptibility

Further sampling has been carried out by the Health Protection Agency [HPA] as part of continued investigations into anti–viral drug susceptibility against seasonal flu viruses currently circulating in Europe. Latest figures show that approximately 14 per cent of the A viruses in Europe have shown resistance to the anti–viral drug, Oseltamivir.

Only a small proportion of samples with this resistance have been identified in the UK, eight –out–of–162 samples tested so far. Although this is an important find, the HPA says it is too early to judge the clinical significance until more research is completed. The HPA continues to work closely with colleagues at the European Centre for Disease Prevention Control and the World Health Organization.

To date, the Oseltamivir resistant A isolates this season have been fully susceptible to the other available anti–viral drugs and there is no need for change to the NICE recommendations for the use of Oseltamivir in the UK at present.

For further information visit the HPA website at: www.hpa.org.uk.

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